五加皮（学名：Eleutherococcus gracilistylus）为五加皮科南五加皮属的植物。根皮入药，称五加皮（南五加皮）。五加皮为五加科落叶小灌木细柱五加和无梗五加干燥的根皮。又名白刺、目骨、追风使、南五加皮等。主产于湖北、湖南、河南、安徽、四川等地。中药五加皮具有祛风湿，补肝肾，强筋骨等功效。《本草纲目》中记载：“补中益气、治风湿痿痹、壮筋骨。”现代研究，本品还具有抗肿瘤、抗疲劳、降低全血粘度、防止动脉粥样硬化形成等作用。五加皮使用方便，煎汤、入丸、散或浸五加皮酒均可，但阴虚火旺者慎用。五加皮还是五加皮酒的简称，在广东地区通常将五加皮酒简称为五加皮，因为虽生产五加皮酒地区众多，但以广州产的最富盛名，岭南一带有“祛湿老友记，广州五加皮”的说法。

Eleutherococcus gracilistylus, also known as Acanthopanax gracilistylus, is deciduous plant which is upright and blue in colour. It is considered a medicine with significant side effects. It is also a widely used Chinese plant. It is in the Araliaceae family in the genus Acanthopanax in the species gracilistylus mainly present at altitude 3000m. They are also in Gaoligonshan Nature Reserve. It is widely distributed in China and has been used as a life-saving medicine against severe cases of paralysis, arthritis and liver disease; several experiments were carried out in 2003. The leaves are 350g.