Framework region

In molecular biology, a framework region is a region in the variable domain of a protein which belongs to the immunoglobulin superfamily, and which is less "variable" than the CDR.

As an example, each chain (alpha or beta) of the TCR is composed of four framework regions, separated by three CDRs.

单词	Framework region
释义	Framework region 英语百科 Framework region In molecular biology, a framework region is a region in the variable domain of a protein which belongs to the immunoglobulin superfamily, and which is less "variable" than the CDR. As an example, each chain (alpha or beta) of the TCR is composed of four framework regions, separated by three CDRs.
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