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单词 GABA agonists
释义

GABA agonists

原声例句
Osmosis-消化

Other choices include prokinetic medications, which increase the tone of the lower esophageal sphincter, and the GABA agonist baclofen, which inhibits transient LES relaxations, especially after meals.

其他选择包括促胃肠动力药,这会增加食管下括约肌的张力,以及GABA激动剂巴氯芬,它能抑制一过性LES松弛,尤其是在饭后。

英语百科

GABA receptor agonist

A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. There are three receptors of the gamma-aminobutyric acid. The two receptors GABA-α and GABA-ρ are ion channels that signal chloride and diminish further action potentials. The GABA-β receptor belongs to the class of G-Protein coupled receptors that inhibit adenylyl cyclase, therefore leading to decreased cyclic adenosine monophosphate (cAMP). GABA-α and GABA-ρ receptors produce sedative and hypnotic effects and have anti-convulsion properties. GABA-β receptors too produce sedative effects. Furthermore they lead to changes in gene transcription.

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更新时间:2025/6/21 19:49:31