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单词 Galactose oxidase
释义

Galactose oxidase

英语百科

Galactose oxidase

Active site structure of galactose oxidase with coordinating ligands shown. The indole ring of Trp290 forms a

Galactose oxidase (D-galactose:oxygen 6-oxidoreductase, D-galactose oxidase, beta-galactose oxidase; abbreviated GAO, GAOX, GOase; EC1.1.3.9) is an enzyme that catalyzes the oxidation of D-galactose in some species of fungi.

Galactose oxidase belongs to the family of oxidoreductases. Copper ion is required as a cofactor for galactose oxidase. A remarkable feature of galactose oxidase is that it is a free radical enzyme. Its catalytic site contains a free radical ligand coordinating to the copper center. This free radical ligand is a covalently cross-linked cysteine and tyrosine side chains that is formed during post-translational modification.

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更新时间:2025/6/21 22:45:15