吉非替尼
Gefitinib (商品名为 Iressa「艾瑞莎」，由AstraZeneca 和 Teva发售。)，被用为治疗乳癌、肺癌和其它癌症。
Gefitinib 是表皮生长因子受体抑制剂 (EGFR inhibitor)，就跟 erlotinib 一样，抑制靶细胞的表皮生长因子受体。它是唯一对表皮生长因子受体突变跟过度表达而产生的癌症的有效药物。
Gefitinib
中文百科
英语百科
Gefitinib 吉非替尼
For the genus of moth see Iressa (moth)
Gefitinib (ZD1839) (INN, /ɡɛˈfɪtᵻnɪb/, trade name Iressa, marketed by AstraZeneca and Teva), is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. However, meta-analyses have not shown any improvement in overall survival, that is, it does not extend life.
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