CAG codes for the amino acid glutamine, so people with Huntington disease patients will have 36 or more glutamines in a row in the huntingtin protein.
因为CAG序列对应的是谷氨酰胺（氨基酸），所以在HD患者体内，huntingtin蛋白质上会有36个以上连续的谷氨酰胺。
glutamine
/'gluːtəmiːn/ /'glʊtəmin/
英汉-汉英词典
n. 谷氨酸盐
词组 | 习惯用语
glutamine synthetase 谷氨酰氨合成酶
英语例句库
- Objective To explore the method of chemical synth esis of L-alanyl-L-glutamine dipeptide.
目的探讨L-丙氨酰-L-谷氨酰胺双肽的化学合成方法。 - carbamoyl phosphate synthetaseⅡ;carbamoyl phosphate synthtase(glutamine hydrolysing);
名称 氨基甲酰磷酸合成酰Ⅱ; - L-Alanyl-L-glutamine(Dipeptiven) was prepared in 10 t/a pilot-plant-scale by using phthalyl method and mixed anhydride method.
以邻苯二甲酰基为保护基,采用混合酸酐法接肽,中试规模制备了L-丙氨酰-L-谷氨酰胺(力肽)。
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原声例句
Osmosis-遗传
Osmosis-神经
The specific way in which extra glutamines causes the disease's symptoms isn't fully understood but the abnormal protein seems to aggregate within the neurons of the cerebellum and the spinal cord, causing them to die.
过多谷氨酰胺导致疾病症状的具体机制尚未完全清楚，但异常蛋白质似乎聚集在小脑和脊髓的神经元内，从而导致神经元的死亡。
Osmosis-神经
In some cases, the involved gene contains a triplet repeat where the nucleotides C, A and G are repeated multiple times in a row and since CAG codes for the amino acid glutamine, the encoded protein will have multiple extra glutamines in a row.
在某些情况下，涉及的基因包含一个三联体重复序列，即核苷酸C、A和G连续重复多次；由于CAG编码谷氨酰胺，编码的蛋白质将具有连续多个额外的谷氨酰胺。
中文百科
谷氨酰胺
谷氨酰胺(Glutamine)亦被称作麸酰胺酸，为人体中含量最丰富的非必需胺基酸，且是唯一一种可直接通过脑血管障壁(BBB)的胺基酸。在人体中保存于骨骼肌或血液中。当受伤或患病时，谷氨酰胺可能需要借由摄取含Gln的食物来获得足够的量。生物体通过谷氨酰胺合成酶催化谷氨酸和铵盐反应生成谷氨酰胺。
英语百科
Glutamine 谷氨醯胺
Glutamine (abbreviated as Gln or Q; encoded by the codons CAA and CAG) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO form under biological conditions), and a side chain amide which replaces the side chain hydroxyl of glutamic acid with an amine functional group, classifying it as a charge neutral, polar (at physiological pH) amino acid. It is non-essential and conditionally essential in humans, meaning the body can usually synthesize sufficient amounts of it, but in some instances of stress, the body's demand for glutamine increases and glutamine must be obtained from the diet.
近义、反义、联想词
近义词
n.amino acid, aminoalkanoic acid
联想词
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