肺出血肾炎综合征("古帕斯捷氏综合征"(Goodpasture syndrome)、GPS、"古帕斯捷氏病"(Goodpasture's disease)、"肺出血肾炎病"、"抗肾小球基底膜抗体病"(anti-glomerular basement antibody disease/anti-GBM antibody disease)，或"抗GBM病"(anti-GBM disease))是一种罕见的自体免疫性疾病，其中抗体攻击肺和肾脏，导致从肺及肾功能衰竭出血。它可能会迅速导致永久性肺、肾损害，经常导致死亡。它配合免疫抑制药物、如皮质类固醇和环磷酰胺一起治疗，并用血浆分离置换法(Plasmapheresis)将其中的抗体从血液中除去。

Goodpasture syndrome (GPS; also known as Goodpasture’s disease, antiglomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture's antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death. It is treated with immunosuppressant drugs such as corticosteroids and cyclophosphamide, and with plasmapheresis, in which the antibodies are removed from the blood. Famous sufferers include Vince Earl, an actor on the British soap opera Brookside, who underwent a successful kidney transplant in 2012.