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单词 Guanine nucleotide exchange factors
释义

Guanine nucleotide exchange factors

英语百科

Guanine nucleotide exchange factor

(重定向自Guanine nucleotide exchange factors)
GDP
Schematic of GEF activation of a GTPase

Guanine nucleotide exchange factors (GEFs) are proteins that activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP). A variety of unrelated structural domains have been shown to exhibit guanine nucleotide exchange activity. Some GEFs can activate multiple GTPases while others are specific to a single GTPase.

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更新时间:2025/6/19 9:15:22