University of California, San Diego, biologist Alysson Muotri. He says researchers have instead relied on animal models.

加州大学圣地亚哥分校的生物学家阿里森·穆特里说到。他表示，研究人员转而依赖动物模型。

A large majority of the studies focusing on brown fat have been conducted in animals or animal models.

大部分关于棕色脂肪的研究都是在动物或动物模型中进行的。

When researchers want to study a disease, one challenge they have is finding out how to recreate the disease in animal models.

当研究者们试图研究某种疾病，面临的挑战之一是如何在动物模型体内重现人类疾病。

Which we did, in preclinical animal models.

我们在临床前动物模型中做到了。

D) Make informed use of animal models.

D) 明智地使用动物模型。

We don't have a perfect animal model.

我们没有完美的动物模型。

He says researchers have instead relied on animal models.

他说，研究人员转而依赖动物模型。

Ferrets Ferrets are the most popular animal model for human influenza.

雪貂 雪貂是最流行的人类流感动物模型。

And I was suddenly like are animal models good for anything?

我突然觉得动物模型有什么用处吗？

So we went to our animal model, and we found three important parts.

所以我们去了我们的动物模型， 我们发现了三个重要的部分。

Research in animal models suggests that the amygdala undergoes changes in size and connectivity during puberty.

动物模型研究表明，杏仁核在青春期的大小和连通性会发生变化。

Aerobic exercise has been shown in many studies to decrease amyloid beta in animal models of the disease.

许多研究表明，有氧运动可以减少疾病动物模型中的淀粉样蛋白 β。

For centuries, scientists have tried to understand them using autopsies, animal models, and, in recent years, imaging techniques.

几个世纪以来，科学家们一直试图通过尸检、动物模型以及近年来的成像技术来了解它们。

Interestingly, giving CBD to our animal models that had a history of self-administering heroin, reduced their heroin-seeking behavior.

有趣的是， 将 CBD 给予我们有自我服用海洛因历史的动物模型，减少了他们寻求海洛因的行为。

We saw this already in the animal models because they are also meant to assess the immune response.

ÖT：我们已经在动物模型中看到了这一点，因为它们也用于评估免疫反应。

Another problem seen in animal models is that misfolded Tau proteins can spread, across synapses, into healthy neurons.

在动物模型中发现的另一个问题是错误折叠的 Tau 蛋白可以通过突触扩散到健康的神经元中。

Getting results from animal models like this is actually the first critical step in the FDA process for developing new medications.

从这样的动物模型中获得结果实际上是 FDA 开发新药过程中的第一个关键步骤。

Because at the moment, I think the FDA in the US requires one small animal model and two large animal model tests for safety.

因为目前， 我认为美国的FDA要求一个小动物模型和两个大动物模型进行安全性测试。

Lipopolysaccharide is something that induces a violent inflammatory response in humans, and is used experimentally to rapidly create inflammation in animal models to study all kinds of inflammatory diseases.

脂多糖是人类产生剧烈炎症反应的诱因，临床用于在动物模型体内快速制造炎症，从而对各类炎性疾病进行研究。

And finally, our aggressiveness can be influenced by our own biochemistry, hormones like testosterone and glucocorticoids and pheromones have all been implicated in animal models of aggression.

最后， 我们的攻击性会受到我们自身生物化学的影响，睾酮、糖皮质激素和信息素等激素都与攻击性动物模型有关。