The antipsychotic drugs used to treat schizophrenia have helped researchers work backwards to trace signatures of the disorder in the brain.

治疗精神分裂症的药物能协助研究者追踪这种病症在大脑中呈现的特征。

Interestingly, one of the most effective antipsychotic drugs, clozapine, is a weak D2 antagonist, suggesting that other neurotransmitter systems like norepinephrine, serotonin, and GABA are involved.

有趣的是，最有效的抗精神病药之一，氯氮平，是一种弱D2受体拮抗剂；这提示其它神经递质系统，比如去甲肾上腺素、5-羟色胺、γ-氨基丁酸也与疾病有关。

STEP 3 See a psychiatrist instead of a family doctor if you're on antidepressants or antipsychotic drugs that may negatively affect your mood and appetite, leading to weight gain.

如果你服用可能会影响你的情绪和食欲，导致体重增加的抗抑郁药物或治疗精神病的药物，看一下精神病医师，而不是家庭医生。

It’s allowed scientists to have the chance at understanding how some antipsychotic drugs bind to their primary molecular target in the human brain.

它让科学家们有机会了解一些抗精神病药物如何与人脑中的主要分子靶标结合。