If our careers have irretrievably faltered, perhaps we can turn to new interests.

如果我们的事业已经无可挽回地摇摇欲坠，也许我们可以转向新的兴趣。

More than 67 billion tons of hard-won stuff was lost, most of it scattered irretrievably.

超过670亿吨来之不易的物资遗失了，大部分四散无踪，不可挽回。

One of the unavoidable frustrations of quantum mechanics is that measuring a particle's position or energy irretrievably alters it.

量子力学一个不可避免的问题是，测量粒子的位置或能量会不可逆转地改变它。

Two of the five-pound notes were now irretrievably dead.

五英镑的钞票中有两张已经无可救药地死了。

I felt so grieved to think that he had gone irretrievably to ruin.

想到他已经无可挽回地走向毁灭， 我感到非常难过。

Have I not irretrievably committed myself? —pride has stood for nothing in the face of my great love.

我不是已经无可挽回地承诺了吗？ ——在我伟大的爱面前， 骄傲毫无意义。

He is a centrist and a determined champion of bipartisanship, vying to lead a coalition that views the Republican Party as irretrievably malignant.

他是一名坚决拥护两党合作的中间派，他要争取的是领导一个认为共和党恶毒得不可救药的联盟的领导权。

If I live, your truth, your reputation, your reward of a life past in sufferings, all that you value is irretrievably lost.

如果我活着， 你的真理，你的名誉，你在苦难中获得的回报， 你所珍视的一切都将无可挽回地失去。

He relieved his overburdened soul with a gusto which left Hopkins hoping that he had not irretrievably put himself in the wrong with the Yard.

他兴致勃勃地释放了自己不堪重负的灵魂， 这让霍普金斯希望他没有无可挽回地让自己在院子里犯错。

'If he were allied to us irretrievably, of course I, or any sensible man, should accept conditions that could not be altered; certainly not be hopelessly melancholy about it.

“如果他与我们不可挽回地结盟， 我，或任何明智的人， 当然应该接受无法改变的条件； 当然不会对此感到无可救药的忧郁。