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单词 kinase
释义

kinase /ˈkɪnˌeɪs//ˈkaɪneɪz/

英汉-汉英词典
n. 激酶,致活酶
词组 | 习惯用语
protein kinase 蛋白激酶
creatine kinase 肌酸激酶
thymidine kinase 胸苷激酶;胸腺嘧啶核苷漱酶
英语例句库
  1. Antiestrogen. Selective protein kinase C (PKC) inhibitor. Induces apoptosis.
    抗雌激素。选择性PKC抑制剂。诱导凋亡。
  2. Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.
    显示细胞生长抑制和细胞毒活性。EGFR激酶抑制剂。有抗血管生成活性。
  3. Altenusin was reported as myosin light chain kinase inhibitor and sphingomyelinase inhibitor.TAN-420E has antitumor activity.
    TAN-420E曾报道有抗肿瘤活性,易氧化为Herbimycin A,后者是很好的除草剂,并具有一定抗菌活性。
  4. Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT).
    摘要NOK能激活包含JAK-STAT信号通路在内的多种促细胞有丝分裂信号通路。
  5. The assay begins with a standard kinase reaction performed in the provided Reaction Buffer with a provided Bisamide Rhodamine 110 peptide substrate (PKA R110 Substrate).
    检测开始时、先用试剂盒提供的PKA双酰胺罗丹明110肽底物进行一个标准的激酶反应。
  6. Uridine-cytidine kinase (UCK) (EC 2.7.1.48) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to UMP and CMP.
    在本论文的第一章中主要是对人类尿苷胞苷激酶(UCK,EC 2.7.1.48)基因进行的一系列研究。

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原声例句
Osmosis-肌骨

Muscle proteins like creatine kinase and myoglobin start leaking out into the bloodstream.

肌肉中的蛋白质,如肌酸激酶与肌红蛋白,会漏入血液中。

健身知识科普

Time to exhaustion, ratings of perceived exertion, heart rate, and fatigue factors, such as serum lactate and creatine kinase levels.

运动至力竭时间,感知体力的评分,心率,疲劳因素,如血清乳酸和肌酸激酶的水平。

名人73个快问快答

Did you know that molecular dynamics can be used to study proteins, enzymes and kinases?

您知道分子动力学可用于研究蛋白质、酶和激酶吗?

经济学人-科技

Xalkori blocks the growth of tumours caused by a mutant form of the gene which encodes a signalling molecule known as anaplastic lymphoma kinase.

Xalkori能够抑制由编码信号分子间变性淋巴瘤激酶基因的突变体所导致的癌细胞的增长。

Osmosis-遗传

The most common type is Non-Homologous End Joining where a protein complex called DNA protein kinase begins by binding to each end of the broken DNA.

最常见的类型是非同源末端连接:一个叫做DNA蛋白激酶的蛋白质复合体首先会结合到断裂的DNA末端。

Osmosis-肌骨

When Rhabdomyolysis develops, the laboratory workup can show elevated levels of creatine kinase and myoglobin, while urinalysis can show tea-colored urine due to high levels of myoglobin.

发生横纹肌溶解时,实验室检查可发现肌酸激酶和肌红蛋白水平升高,尿检可见由肌红蛋白升高导致的茶色尿。

医学之光:人类与疾病的斗争

Laboratory results on hospital days 3 and 5 (illness days 7 and 9) reflected leukopenia, mild thrombocytopenia, and elevated levels of creatine kinase (Table 1).

住院第 3 天和第 5 天(发病第 7 天和第 9 天)的实验室结果反映出白细胞减少、轻度血小板减少和肌酸激酶水平升高(表 1)。

健身知识科普

Same goes for indirect muscle recovery markers, like creatine kinase and muscle voluntary isometric force contraction, where active cooldowns don't seem to change much of these recovery factors.

此结果同样在测量间接肌肉恢复的标志物中成立,例如,肌酸激酶活性和肌肉自发等长收缩力,主动冷身不会对这些恢复因素造成影响。

Osmosis-肌骨

Over time, cellular proteins like creatine kinase, or CK, start escaping the damaged cell and calcium starts to enter the cell, and this ultimately leads to cell death.

时间一长,如肌酸激酶(CK)等细胞蛋白开始从受损细胞中逸出,而钙离子开始进入细胞,这最终造成细胞死亡。

Scishow 精选系列

See, phorbols mimic the action of diacylglycerol — a fatty molecule your body uses in a number of ways, including to activate an enzyme called protein kinase C, or PKC for short.

因为佛波醇类模拟了二酰基甘油的活动,二酰基甘油这种脂肪分子在你的身体里有很多作用,它能激活一种蛋白激酶C,简称PKC。

中文百科

激酶

在生物化学里,激酶是一类从高能供体分子(如ATP)转移磷酸基团到特定靶分子(受质)的酶;这一过程谓之磷酸化。

一般而言,磷酸化的目的是“激活”或“能化”受质,增大它的能量,以使其可参加随后的自由能负变化的反应。所有的激酶都需要存在一个二价金属离子(如Mg或Mn),该离子起稳定供体分子高能键的作用,且为磷酸化的发生提供可能性。

英语百科

Kinase 激酶

Dihydroxyacetone kinase in complex with a non-hydrolyzable ATP analog (AMP-PNP). Coordinates from PDB ID:1UN9.[1]
General reaction that is catalyzed by kinases.
Overview of signal transduction pathways. Many of the proteins involved are kinases, including protein kinases (such as MAPK and JAK) and lipid kinases (such as PI3K).
A variety of mitogenic signals engage the MAPK pathway and promote cell growth and differentiation through a kinase cascade.

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates. This process is known as phosphorylation, where the substrate gains a phosphate group and the high-energy ATP molecule donates a phosphate group. This transesterification produces a phosphorylated substrate and ADP. Conversely, it is referred to as dephosphorylation when the phosphorylated substrate donates a phosphate group and ADP gains a phosphate group (producing a dephosphorylated substrate and the high energy molecule of ATP). These two processes, phosphorylation and dephosphorylation, occur four times during glycolysis. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which catalyze the addition of inorganic phosphate groups to an acceptor, nor with phosphatases, which remove phosphate groups. The phosphorylation state of a molecule, whether it be a protein, lipid, or carbohydrate, can affect its activity, reactivity, and its ability to bind other molecules. Therefore, kinases are critical in metabolism, cell signalling, protein regulation, cellular transport, secretory processes, and many other cellular pathways.

近义、反义、联想词
近义词
n.
enzyme

联想词
phosphatase磷酸酶;phosphorylation磷酸化作用;tyrosine酪氨酸;synthase合酶;dehydrogenase脱氢酶;inhibitor抑制物;receptor受体;protease蛋白酶;inhibitors抗化剂;enzyme酶;protein蛋白质;
英英词典
kinase n.
  1. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
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更新时间:2025/6/20 20:12:20