伊利湖（Lake Erie）是北美洲五大湖之一，也是世界第十三大湖。伊利湖的名字来源于原在南岸定居的印地安伊利部落。

伊利湖的面积有24,000平方公里，平均深度19米，蓄水量483立方公里。底特律河（Detroit River）将休伦湖水导向这里，而尼亚加拉河（Niagara River）经尼亚加拉瀑布将湖水引入安大略湖。湖的南岸是美国的俄亥俄州、宾夕法尼亚州和纽约州，西岸是密歇根州，北岸是加拿大的安大略省。

Lake Erie (/ˈɪəri/; French:Lac Érié) is the fourth largest lake (by surface area) of the five Great Lakes in North America, and the thirteenth largest globally if measured in terms of surface area. It is the southernmost, shallowest, and smallest by volume of the Great Lakes and therefore also has the shortest average water residence time. At its deepest point Lake Erie is 210 feet (64 metres) deep. Lake Erie's northern shore is bounded by the Canadian province of Ontario, with US states of Ohio, Pennsylvania and New York on its southern and easternmost shores and Michigan on the west. These jurisdictions divide the surface area of the lake by water boundaries. The lake was named by the Erie tribe of Native Americans who lived along its southern shore. That Iroquoian tribe called it "Erige" ("cat") because of its unpredictable and sometimes violently dangerous nature. It is a matter of conjecture whether the lake was named after the tribe, or if the tribe was called "Erie" because of its proximity to the lake.