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单词 Minimotif
释义

Minimotif

英语百科

Short linear motif

The Human papilloma virus E7 oncoprotein mimic of the LxCxE motif (red) bound to the host Retinoblastoma protein (dark grey)(PDB: 1gux​)
MDM2 SWIB domain-binding motif mimic drug Nutlin bound to MDM2(PDB: 3lbk​)

In molecular biology Short Linear Motifs (also known as SLiMs, Linear Motifs or minimotifs) are short stretches of protein sequence that mediate protein protein interaction.

The first definition was given by Tim Hunt:

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更新时间:2025/6/21 12:48:58