He has neuroblastoma cancer which has recurred for a third time.

他患有神经母细胞瘤，这已经是第三次复发了。

A poorly differentiated neuroblastoma is composed of slightly more differentiated cells, with smaller nuclei and a bit more cytoplasm.

分化不良型神经母细胞瘤由分化稍多一些的细胞组成，有较小的细胞核和多一点的细胞质。

Symptoms of neuroblastoma result from the chemokine release, and include fever, weight loss, sweating, and fatigue.

神经母细胞瘤症状的产生源于趋化因子的释放，包括发热、体重减轻、出汗和乏力。

Generally speaking, the best treatment outcomes are among the youngest patients that have a differentiating neuroblastoma.

一般来说，年龄小且是分化型肿瘤的病人治疗效果最好。

About half of all neuroblastomas spread to the bones, causing bone pain and small fractures.

大约一半的神经母细胞瘤会转移到骨骼，造成骨痛和轻微骨折。

A touching example of this was when Jermain Defoe walked out with the then-six-year-old Bradley Lowery who was diagnosed with neuroblastoma.

一个感人的例子是，杰梅因·迪福和当时六岁的布拉德利·洛里一起出场，当时他被诊断患有成神经细胞瘤。

When any type of neuroblastoma forms, cells in the surrounding tissue release chemokines called CXCL12 and that stimulates nearby immune cells.

无论哪种神经母细胞瘤形成，周围组织的细胞都会释放CXCL12趋化因子，激活附近的免疫细胞。

Finally, a differentiating neuroblastoma is composed of cells with lots of cytoplasm, and is often surrounded by a substance called Schwannian stroma.

分化型神经母细胞瘤的组成细胞有大量细胞质，并且常被一种叫做Schwannian基质的物质包围。

High levels of HMA and VMA are usually the first indication of neuroblastoma.

高水平的HMA和VMA通常是神经母细胞瘤的早期征象。

Other symptoms of neuroblastoma depend on where the tumor is located, and are usually a result of the tumor pressing up against surrounding organs.

还有一些症状取决于肿瘤的位置，常常由肿瘤压迫周围器官而产生。