Paget's disease of bone

（重定向自Paget disease of bone）

The Ugly Duchess - portrait by Quentin Matsys. Michael Baum, emeritus professor of surgery at University College London, suggested that the sitter had Paget's disease of bone.[4]

Micrograph showing Paget's disease of the bone with the characteristic jigsaw puzzle-like/mosaic pattern, H&E stain

Paget's disease of right coxa. Man of 80 years age.

Paget's disease of bone (also termed osteitis deformans or, ambiguously, just Paget's disease; "Paget" is pronounced /ˈpædʒᵻt/) is a chronic disorder that can result in enlarged and misshapen bones. Paget's is caused by the excessive breakdown and formation of bone, followed by disorganized bone remodeling. This causes affected bone to weaken, resulting in pain, misshapen bones, fractures and arthritis in the joints near the affected bones. Rarely, it can develop into a primary bone cancer known as Paget's sarcoma. Often Paget's disease is localized to only a few bones in the body. The pelvis, femur, and lower lumbar vertebrae are the most commonly affected bones. Paget's disease typically is localized, affecting just one or a few bones, as opposed to osteoporosis, for example, which usually affects all the bones in the body.

单词	Paget disease of bone
释义	Paget disease of bone 英语百科 Paget's disease of bone （重定向自Paget disease of bone） Paget's disease of bone (also termed osteitis deformans or, ambiguously, just Paget's disease; "Paget" is pronounced /ˈpædʒᵻt/) is a chronic disorder that can result in enlarged and misshapen bones. Paget's is caused by the excessive breakdown and formation of bone, followed by disorganized bone remodeling. This causes affected bone to weaken, resulting in pain, misshapen bones, fractures and arthritis in the joints near the affected bones. Rarely, it can develop into a primary bone cancer known as Paget's sarcoma. Often Paget's disease is localized to only a few bones in the body. The pelvis, femur, and lower lumbar vertebrae are the most commonly affected bones. Paget's disease typically is localized, affecting just one or a few bones, as opposed to osteoporosis, for example, which usually affects all the bones in the body.
随便看	rear expansion sheet的意思 rear face的意思 rearface的意思 rear face of flight的意思 Rear Fanged snake的意思 rear farm tire的意思 rear farm tyre的意思 rearfeet的意思 rear fender的意思 rear fin的意思 rear finder的意思 rear fire box head的意思 rear flank的意思 rear flank defender的意思 rear flap的意思 rear floor mat的意思 rear foci的意思 rear focus的意思 Rear fog lamp的意思 rear fog lamp, rear light的意思 rear fog light的意思 rearfoot的意思 rear foot的意思 rear frame的意思 rear frame member的意思