苯乙醇胺N-甲基转移酶 Phenylethanolamine N-methyltransferase
（重定向自PNMT）
苯基乙醇胺N-甲基转移酶（英语：Phenylethanolamine N-methyltransferase；PNMT）是一个存在于肾上腺髓质的酶，其将去甲肾上腺素转换为肾上腺素。
此酶受皮质醇的正影响，后者由肾上腺皮质产生出来。
S-腺苷-L-甲硫氨酸（SAM）是一个需要用的辅因子。
PNMT
中文百科
英语百科
Phenylethanolamine N-methyltransferase 苯乙醇胺N-甲基转移酶
（重定向自PNMT）
![This is a representation of the disulfide bond made between monomers of PNMT. It was made using Chimera and 4MQ4.[1]This is a model of the active site of PNMT showing both the distance between amino and sulfur groups, and a proposed area for methyl transfer. It was made using Chimera and 4MQ4.[1]](/uploads/202502/03/PNMT_Cysteine_Disulfide_Bond1626.png)
![Human biosynthesis pathway for trace amines and catecholamines[8][9]
L-Phenylalanine
L-Tyrosine
L-Dopa
Epinephrine
Phenethylamine
p-Tyramine
Dopamine
Norepinephrine
N-Methylphenethylamine
N-Methyltyramine
p-Octopamine
Synephrine
3-Methoxytyramine
AADC
AADC
AADC
PNMT
PNMT
PNMT
PNMT
AAAH
AAAH
COMT
DBH
DBH
PNMT plays an important role in trace amine and catecholamine biosynthesis.](/uploads/202502/03/Catecholamine_and_trace_amine_biosynthesis1626.png)
Phenylethanolamine N-methyltransferase (PNMT) is an enzyme found in the adrenal medulla that converts norepinephrine (noradrenaline) to epinephrine (adrenaline).
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