普雷布尔县（Preble County, Ohio）是美国俄亥俄州西南部的一个县，西邻印地安纳州。面积1,104平方公里。根据美国2000年人口普查，共有人口42,337人。县治伊顿 (Eaton)。

成立于1808年2月15日。县名纪念美国独立战争、的黎波里战争时期海军军官爱德华·普雷布尔 (Edward Preble)。

Preble County is a county located in the U.S. state of Ohio. As of the 2010 census, the population was 42,270. Its county seat is Eaton. The county was formed on February 15, 1808 from portions of Butler and Montgomery Counties. It is named for Edward Preble, a naval officer who fought in the American Revolutionary War and against the Barbary Pirates.