普罗富莫事件（英文：Profumo Affair）是一件发生于1963年的英国政治丑闻，该丑闻以事件主角，时任陆军大臣的约翰·普罗富莫命名。

普罗富莫原是一名受重视的保守党内阁成员，他的妻子是女演员瓦莱莉娅·霍布森（Valerie Hobson）。而丑闻之焦点在于普罗富莫和歌舞演员克莉丝汀·基勒（Christine Keeler）发生的一段婚外情。在1961年，当时伦敦有名的整骨医生斯蒂芬·沃德（Stephen Ward）在克莱芙顿（Cliveden）举行派对，普罗富莫和基勒就是在那里认识的，但他们俩的关系只维持了数星期便告吹。然而，有关他们绯闻的谣言却在1962年开始在公众间流传，而令人惊讶的是，原来基勒更曾同时与一位苏联驻伦敦大使馆的高级海军武官，叶夫根尼·伊凡诺夫（Yevgeny Ivanov）有染（伊凡诺夫是苏联间谍）。

The Profumo affair was a British political scandal that originated with a brief sexual relationship in 1961 between John Profumo, the Secretary of State for War in Harold Macmillan's government, and Christine Keeler, a 19-year-old would-be model. In March 1963, Profumo denied any impropriety in a personal statement to the House of Commons, but was forced to admit the truth a few weeks later. He resigned from the government and from Parliament. The repercussions of the affair severely damaged Macmillan's self-confidence, and he resigned as prime minister on health grounds in October 1963. His Conservative Party was marked by the scandal, which may have contributed to its defeat by Labour in the 1964 general election.