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单词 Psychological Addiction
释义

Psychological Addiction

原声例句
美国生活Podcast

People talk about the physical addiction to nicotine and the psychological addiction to nicotine.

人们谈论尼古丁的身体成瘾和尼古丁的心理成瘾。

Asap SCIENCE 精选

Though it's a psychological addiction as opposed to a substance addiction, brain scans of these people actually show a similar impairment of regions that those with drug dependence have.

虽然这是心理成瘾而不是物质成瘾,但是扫描他们的大脑后发现,脑内损伤的区域和药物依赖者损伤的区域类似。

AsapSCIENCE - Tech

Though it’s a psychological addiction as opposed to a substance addiction, brain scans of these people actually show a similar impairment of regions that those with drug dependence have.

虽然这是一种心理成瘾而不是物质成瘾,但对这些人的脑部扫描实际上显示出与药物依赖者相似的区域损伤。

中文百科

成瘾 Addiction

(重定向自Psychological Addiction)
一个人在伊朗城市内沙布尔,可能吸毒。
El alcohol y el tabaco son las adicciones más comunes.


Signaling cascade in the nucleus accumbens that results in psychostimulant addiction

 
 

Note: colored text contains article links.

Nuclear pore
Nuclear membrane
Plasma membrane

Cav1.2
NMDAR
AMPAR
DRD1
DRD5
DRD2
DRD3
DRD4

Gs
Gi/o
cAMP
cAMP
PKA

CaM
CaMKII
DARPP-32
PP1
PP2B

CREB
ΔFosB
JunD
c-Fos
SIRT1
HDAC1

[Color legend 1]


This diagram depicts the signaling events in the brain's reward center that are induced by chronic high-dose exposure to psychostimulants that increase the concentration of synaptic dopamine, like amphetamine, methamphetamine, and phenethylamine. Following presynaptic dopamine and glutamate co-release by such psychostimulants,[35][36] postsynaptic receptors for these neurotransmitters trigger internal signaling events through a cAMP pathway and calcium-dependent pathway that ultimately result in increased CREB phosphorylation.[37][38][39]  Phosphorylated CREB increases levels of ΔFosB, which in turn represses the c-Fos gene with the help of corepressors;[38] c-Fos repression acts as a molecular switch that enables the accumulation of ΔFosB in the neuron.[40] A highly stable (phosphorylated) form of ΔFosB, one that persists in neurons for one or two months, slowly accumulates following repeated high-dose exposure to stimulants through this process.[41][42] ΔFosB functions as

成瘾英语:Addiction)是指一种重复性的强迫行为,即使这些行为已知可能造成不良后果的情形下,仍然被持续重复。这种行为可能因中枢神经系统功能失调造成,重复这些行为也可以反过来造成神经功能受损。

瘾被用于描述精神强迫或者过度的心理依赖,例如物质依赖,药物滥用(即俗称的滥药、毒瘾)、酒瘾、烟瘾、性瘾。或是持续出现特定行为(赌、暴食),网瘾、赌瘾、官瘾、财迷、工作狂、暴食症、色情狂、跟踪狂、偷窃狂、整形迷恋及购物狂等,是生理或者心理上,甚至是同时具备的一种依赖症。

英语百科

Addiction 成瘾

(重定向自Psychological Addiction)


Signaling cascade in the nucleus accumbens that results in psychostimulant addiction

 
 

Note: colored text contains article links.

Nuclear pore
Nuclear membrane
Plasma membrane

Cav1.2
NMDAR
AMPAR
DRD1
DRD5
DRD2
DRD3
DRD4

Gs
Gi/o
cAMP
cAMP
PKA

CaM
CaMKII
DARPP-32
PP1
PP2B

CREB
ΔFosB
JunD
c-Fos
SIRT1
HDAC1

[Color legend 1]


This diagram depicts the signaling events in the brain's reward center that are induced by chronic high-dose exposure to psychostimulants that increase the concentration of synaptic dopamine, like amphetamine, methamphetamine, and phenethylamine. Following presynaptic dopamine and glutamate co-release by such psychostimulants,[35][36] postsynaptic receptors for these neurotransmitters trigger internal signaling events through a cAMP pathway and calcium-dependent pathway that ultimately result in increased CREB phosphorylation.[37][38][39]  Phosphorylated CREB increases levels of ΔFosB, which in turn represses the c-Fos gene with the help of corepressors;[38] c-Fos repression acts as a molecular switch that enables the accumulation of ΔFosB in the neuron.[40] A highly stable (phosphorylated) form of ΔFosB, one that persists in neurons for one or two months, slowly accumulates following repeated high-dose exposure to stimulants through this process.[41][42] ΔFosB functions as
Top: this depicts the acute expression of various Fos family proteins following an initial exposure to an addictive drug.Bottom: this illustrates increasing ΔFosB expression from repeated twice daily drug binges, where these phosphorylated (35–37 kD) ΔFosB isoforms persist in mesolimbic dopamine neurons for up to 2 months.[52][42]

Addiction is a medical condition that is characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. It can be thought of as a disease or biological process leading to such behaviors. The two properties that characterize all addictive stimuli are that they are reinforcing (i.e., they increase the likelihood that a person will seek repeated exposure to them) and intrinsically rewarding (i.e., something perceived as being positive or desirable).

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更新时间:2025/6/21 7:48:14