Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.

SNRNP基因易位会破坏小核内核糖核蛋白（SNRPN），并将核仁小RNA基因移出印记中心，导致这些基因的甲基化沉默。