圣克鲁斯德约霍阿是洪都拉斯的城镇，位于该国西北部，由科尔特斯省负责管辖，始建于1864年，面积733.64平方公里，海拔高度486米，2001年人口61,461，人口密度每平方公里83.78人。

Santa Cruz de Yojoa is a municipality in the Honduran department of Cortés.

Santa Cruz de Yojoa is located approximately 50 miles south of San Pedro Sula on top of a large hillside on the way to the dam that supplies power to many Central American cities. Santa Cruz de Yojoa, over the years, has become a large populated city, with its central park known as "Parque Central de Santa Cruz de Yojoa" which translated into English means "Santa Cruz de Yojoa Central Park". SCDY is home to 2 churches, one being Catholic and the other Christian of a different denomination. Santa cruz owns more than 10 transportation buses which have its route through Santa Cruze's only paved street. 1 of said buses are stored in SCDY's main hotel, Los Amigos hotel.