圣蒂尔苏（Santo Tirso），是葡萄牙波尔图区的一个城市。

市镇总面积136.60平方公里，市镇总人口71 530（2011年）。圣蒂尔苏市镇共包含14个堂区。

Santo Tirso (Portuguese pronunciation: [ˈsɐ̃tu ˈtiɾsu]) is a city and municipality located in the north of Porto Metropolitan Area, Porto District, Portugal. In the region, the Ave Valley, there is a large center of textile industry. The population in 2011 was 71,530, in an area of 136.60 km².