哈特里－福克方程序（英语：Hartree–Fock equation），又称为HF方程，是一个应用变分法计算多电子系统波函数的方程序，是量子物理、凝聚态物理学、量子化学中最重要的方程之一。该计算思路也称为“哈特里－福克方法”（Hartree–Fock method）。

基于分子轨道理论的所有量子化学计算方法都是以HF方程为基础的，鉴于分子轨道理论在现代量子化学中的广泛应用，HF方程可以被称作现代量子化学的基石。

In computational physics and chemistry, the Hartree–Fock (HF) method is a method of approximation for the determination of the wave function and the energy of a quantum many-body system in a stationary state.

The Hartree–Fock method often assumes that the exact, N-body wave function of the system can be approximated by a single Slater determinant (in the case where the particles are fermions) or by a single permanent (in the case of bosons) of N spin-orbitals. By invoking the variational method, one can derive a set of N-coupled equations for the N spin orbitals. A solution of these equations yields the Hartree–Fock wave function and energy of the system.