Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT).
摘要NOK能激活包含JAK-STAT信号通路在内的多种促细胞有丝分裂信号通路。
Signaling pathways
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That finding confirms the important role these signaling pathways play in dental development.
该研究结果确认了这些信号通路在牙齿发育过程中起到的重要作用。
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So the neuro science project I'm working on involves the cellular signaling pathway of neuronal nitric oxide synthase.
我在做的这个神经学科项目涉及神经元一氧化氮合酶细胞信号传导通路。
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And as people gain weight, damaged to signaling pathways makes it increasingly difficult for the brain to measure food intake and fat storage.
随着人们体重增加，信号通路受损使得大脑越来越难以测量食物摄入和脂肪储存。
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Signal transduction
![An overview of integrin-mediated signal transduction, adapted from Hehlgens et al. (2007).[34]](/uploads/202502/11/Integrin_sig_trans_overview5523.jpeg)
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, eventually eliciting a response. Depending on the cell, the response may alter the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can generate a response involving hundreds to millions of molecules.
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