The tetanospasmin destroys the rails so that the trains can't move.

破伤风痉挛毒素破坏了铁路，导致列车无法运行。

Tetanus is usually treated with tetanus immune globulin or TIG, which is an antitoxin that binds to circulating tetanospasmin.

破伤风可使用破伤风免疫球蛋白（TIG）治疗；TIG是一种能够特异性结合破伤风痉挛毒素的抗毒素。

Clostridium tetani is notorious for one of its toxins called tetanospasmin, which can severely disrupt the neuromuscular system of mammals.

破伤风梭菌因其产生的破伤风痉挛毒素而臭名昭着，该毒素严重影响哺乳动物的神经肌肉系统。

Once they get inside, tetanospasmin cleaves SNARE proteins, which are proteins that pull vesicles that are loaded with neurotransmitters to the neuron membrane.

一旦进入，破伤风痉挛毒素将剪切SNARE蛋白；SNARE蛋白能够将装有神经递质的囊泡拉向神经细胞膜。

One example is tetanus: its symptoms are not caused by the Clostridium tetani bacterium, but by a neurotoxin it produces (tetanospasmin).

一个例子是破伤风：它的症状不是由破伤风梭菌引起的， 而是由它产生的一种神经毒素（破伤风痉挛素）引起的。

All right as a quick recap, Clostridium tetani is a sporulating, gram-positive, bacillus anaerobe that makes the toxin tetanospasmin, which causes tetanus by disrupting the release of inhibitory neurotransmitters from Renshaw cells.

得！快速复习一下：破伤风梭菌是一种产芽孢的革兰氏阳性厌氧棒状杆菌，能够产生引起破伤风的罪魁祸首破伤风痉挛毒素；该毒素通过干扰闰绍细胞中抑制性神经递质的释放而致病。