Beta thalassemia

Protein HBB PDB 1a00: this is a healthy Beta Globin Protein

Surgically removed spleen of a Thalassemic child. It is about 15 times larger than normal.

Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals. Global annual incidence is estimated at 1 in 100,000. Beta thalassemia (β thalassemia) is a form of thalassemia caused by mutations in the HBB gene on chromosome 11, inherited in an autosomal recessive fashion. The severity of the disease depends on the nature of the mutation.

单词	Beta thalassemia
释义	Beta thalassemia 原声例句连线杂志 These are diseases like sickle cell anemia or beta thalassemia. 比如镰状细胞性贫血或β地中海贫血。英语百科 Beta thalassemia Beta thalassemias (β thalassemias) are a group of inherited blood disorders. They are caused by reduced or absent synthesis of the beta chains of hemoglobin that result in variable outcomes ranging from severe anemia to clinically asymptomatic individuals. Global annual incidence is estimated at 1 in 100,000. Beta thalassemia (β thalassemia) is a form of thalassemia caused by mutations in the HBB gene on chromosome 11, inherited in an autosomal recessive fashion. The severity of the disease depends on the nature of the mutation.
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