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单词 Tyrosine hydroxylase
释义

Tyrosine hydroxylase

英语例句库

Such graft-derived functional effects were accompanied by preservation of tyrosine hydroxylase (TH) immunoreactivity along the nigrostriatal pathway.

黑质纹状体通路上酪氨酸羟化酶免疫活性可随移植衍生物机能效应得以保存。

原声例句
医学英语视频

First, with the help of enzyme tyrosine hydroxylase (TH), tyrosine gets converted to L-dopa, also known as levodopa.

首先,在酪氨酸羟化酶(TH)的帮助下,酪氨酸也转化为左旋多巴被称为左旋多巴。

中文百科

酪氨酸羟化酶

酪氨酸羟化酶催化酪氨酸生成二羟基苯丙氨酸

酪氨酸羟化酶英语:Tyrosine hydroxylase)或酪氨酸3-单加氧酶英语:tyrosine 3-monooxygenase)是负责催化氨基酸L-酪氨酸转变为二羟基苯丙氨酸(多巴)的酶。因此它使用四氢生物蝶呤作为辅酶。多巴是多巴胺的一个前体,相应地,后者亦是去甲肾上腺素与肾上腺素的前体。在人体中,酪氨酸羟化酶由TH基因编码出来。

英语百科

Tyrosine hydroxylase 酪氨酸羟化酶

Tyrosine hydroxylase from rat showing two of its domains, the tetramerization domain (pink) and the catalytic domain (blue). The regulatory domain (not shown) would sit somewhere on the right hand side of the image where also the enzyme's substrate would enter from.
Tyrosine hydroxylase catalyzes the rate limiting step in catecholamine biosynthesis

Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecular oxygen (O2), as well as iron (Fe) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines. In humans, tyrosine hydroxylase is encoded by the TH gene, and the enzyme is present in the central nervous system (CNS), peripheral sympathetic neurons and the adrenal medulla. Tyrosine hydroxylase, phenylalanine hydroxylase and tryptophan hydroxylase together make up the family of aromatic amino acid hydroxylases (AAAHs).

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更新时间:2025/6/18 4:44:10