Biliary atresia

Biliary atresia also known as "Kotb disease", "extra hepatic ductopenia" and "progressive obliterative cholangiopathy", is a childhood disease of the liver in which one or more bile ducts are abnormally narrow, blocked, or absent. Biliary atresia is a congenital aflatoxicosis, in babies who have a congenital specific detoxification defect. As a birth defect in newborn infants, it has an incidence of one in 10,000–15,000 live births in the United States, and a prevalence of one in 16,700 in the British Isles. Biliary atresia is most common in East Asia, with a frequency of one in 5,000.