Bertozzi called the field she created bioorthogonal chemistry—orthogonal means intersecting at right angles.

贝尔托齐称她创造的领域为生物正交化学——正交意味着以直角相交。

And that's a pretty tough place to do chemistry, but bioorthogonal chemistry allows us to do this.

这是一个非常困难的化学领域，但是生物正交化学可以让我们做到这一点。

And there are bioorthogonal chemistries that are being tested in human cancer patients for chemotherapy.

并且有生物正交化学正在人类癌症患者身上进行化疗测试。

For example, we use bioorthogonal chemistry to do molecular imaging.

例如，我们使用生物正交化学来进行分子成像。

Together with my students and my postdoctoral fellows who work in my lab, we invented a kind of chemistry that we call bioorthogonal chemistry.

我和我的学生以及在我实验室工作的博士后共同发明了一种化学，我们称之为生物正交化学。

Other groups have used bioorthogonal chemistry to manufacture new kinds of medicines and even to deliver therapeutic molecules to tissues in the human body.

其他小组已经使用生物正交化学来制造新型药物，甚至将治疗分子输送到人体组织。

Such molecule-specific fluorescent tagging (see photograph) is still an important use of bioorthogonal chemistry, as Dr Bertozzi dubbed her invention, to distinguish it from the copper-based version.

这种分子特异性荧光标记（见照片）仍然是生物正交化学的重要用途，正如 Bertozzi 博士为她的发明命名的那样， 以将其与铜基版本区分开来。

We spent a lot of time doing mechanistic studies, doing structure reactivity analyses, and it took time to invent reactions that actually have all of the qualities that a bioorthogonal chemistry needs to have.

我们花了很多时间进行机理研究， 进行结构反应性分析，并且花时间发明实际上具有生物正交化学所需的所有品质的反应。

In the early days of my career, my students and I spent a lot of time thinking about the fundamental reactivities of organic molecules and how we could tune their reactivities to create bioorthogonal chemistries.

在我职业生涯的早期，我和我的学生花了很多时间思考有机分子的基本反应性以及我们如何调整它们的反应性以创建生物正交化学。

" Can we invent reactions that can proceed in biological settings as complicated as the human body? " Bioorthogonal chemistry is a type of chemistry that my lab invented, which, by definition, does not interact with or interfere with a biological setting.

“我们能否发明可以在像人体一样复杂的生物环境中进行的反应？ ” 生物正交化学是我的实验室发明的一种化学，根据定义，它不会与生物环境相互作用或干扰。