Bispecific monoclonal antibody

Three types of bispecific antibodies: trifunctional antibody, chemically linked Fab and bi-specific T-cell engager (bottom row). Parts of the two different antibodies are coloured blue and green, respectively.

The mechanism of action of a BsMAb, exemplified by catumaxomab, representing the first approved bispecific trifunctional antibody.

A bispecific monoclonal antibody (BsMAb, BsAb) is an artificial protein that is composed of fragments of two different monoclonal antibodies and consequently binds to two different types of antigen. The most widely used application of this approach is in cancer immunotherapy, where BsMAbs are engineered that simultaneously bind to a cytotoxic cell (using a receptor like CD3) and a target like a tumour cell to be destroyed.

单词	Bispecific monoclonal antibody
释义	Bispecific monoclonal antibody 英语百科 Bispecific monoclonal antibody A bispecific monoclonal antibody (BsMAb, BsAb) is an artificial protein that is composed of fragments of two different monoclonal antibodies and consequently binds to two different types of antigen. The most widely used application of this approach is in cancer immunotherapy, where BsMAbs are engineered that simultaneously bind to a cytotoxic cell (using a receptor like CD3) and a target like a tumour cell to be destroyed.
随便看	blueberry yogurts的意思 blue bice的意思 bluebill的意思 bluebill的意思 blue billy的意思 blue bind的意思 bluebird的意思 blue bird的意思 bluebird的意思 Blue Birds的意思 Blue Black的意思 Blueblack的意思 blueblack ink的意思 blue black ink的意思 blue black level的意思 blue blanket的意思 blue blazers的意思 blueblind的意思 blue blindness的意思 blueblindness的意思 blue bloated type的意思 Blue bloater的意思 blue blood的意思 Blueblood的意思 blue blood的意思