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单词 Addictive drugs
释义

Addictive drugs

原声例句
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Yeah, there's nothing quite like a steaming cup full of an addictive drug in the morning.

是呀,没有什么比得上早晨来一整杯热呼呼让人上瘾的毒品。

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Well, the key neurochemical behind addiction is dopamine as all addictive drugs cause a massive rise in dopamine.

成瘾背后的关键神经化学物质就是多巴胺,正如所有成瘾药物都会导致巨量多巴胺上升。

双语版 TED-Ed 演讲精选

Like all addictive drugs, it prompts a squirt of dopamine in the nucleus accumbens which gives users a surge of pleasure.

和所有成瘾性药物一样,酒精可以提升伏隔核中的多巴胺含量,使饮用者产生愉悦感。

经济学人-科技

It may be possible to vaccinate people against addictive drugs THE idea of vaccinating drug addicts against their affliction is an intriguing one.

人们也许能通过疫苗来阻止成瘾药物的使用对药物滥用者进行免疫来对抗他们受到的折磨是一个吸引人的课题。

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That can happen with any addictive drug.

任何成瘾药物都可能发生这种情况。

11.Around the World in 80 Days(29篇完结)

Opium is a highly addictive drug made from poppies.

鸦片是一种由罂粟制成的高度成瘾性药物。

长喜英语_大学英语六级考试_读美文记单词

Yet, unlike the classic addictive drugs, Ecstasy does not produce physical withdrawal symptoms.

但和传统上瘾药不同,停止服用摇头丸后不会产生任何身体上的戒断症状。

TED演讲(音频版)精选

And it is that smartphones come equippedwith some of the most addictive drugs that humanity has ever engineered.

智能手机配备了一些人类有史以来最容易上瘾的药物。

Reading Explorer 2

In this way, it is in fact an addictive drug, one that doctors recommend we all cut down on.

通过这种方式, 它实际上是一种令人上瘾的药物, 医生建议我们都减少使用。

Sway

And the reason I wanted to look at a legal drug that almost all of us are involved with, caffeine, is to look at why this powerful and addictive drug has been, for most of its history, celebrated.

我之所以想研究一种我们几乎所有人都接触过的合法药物,咖啡因, 是为了研究为什么这种强大且令人上瘾的药物在其历史的大部分时间里都受到庆祝。

中文百科

成瘾 Addiction

(重定向自Addictive drugs)
一个人在伊朗城市内沙布尔,可能吸毒。
El alcohol y el tabaco son las adicciones más comunes.


Signaling cascade in the nucleus accumbens that results in psychostimulant addiction

 
 

Note: colored text contains article links.

Nuclear pore
Nuclear membrane
Plasma membrane

Cav1.2
NMDAR
AMPAR
DRD1
DRD5
DRD2
DRD3
DRD4

Gs
Gi/o
cAMP
cAMP
PKA

CaM
CaMKII
DARPP-32
PP1
PP2B

CREB
ΔFosB
JunD
c-Fos
SIRT1
HDAC1

[Color legend 1]


This diagram depicts the signaling events in the brain's reward center that are induced by chronic high-dose exposure to psychostimulants that increase the concentration of synaptic dopamine, like amphetamine, methamphetamine, and phenethylamine. Following presynaptic dopamine and glutamate co-release by such psychostimulants,[35][36] postsynaptic receptors for these neurotransmitters trigger internal signaling events through a cAMP pathway and calcium-dependent pathway that ultimately result in increased CREB phosphorylation.[37][38][39]  Phosphorylated CREB increases levels of ΔFosB, which in turn represses the c-Fos gene with the help of corepressors;[38] c-Fos repression acts as a molecular switch that enables the accumulation of ΔFosB in the neuron.[40] A highly stable (phosphorylated) form of ΔFosB, one that persists in neurons for one or two months, slowly accumulates following repeated high-dose exposure to stimulants through this process.[41][42] ΔFosB functions as

成瘾英语:Addiction)是指一种重复性的强迫行为,即使这些行为已知可能造成不良后果的情形下,仍然被持续重复。这种行为可能因中枢神经系统功能失调造成,重复这些行为也可以反过来造成神经功能受损。

瘾被用于描述精神强迫或者过度的心理依赖,例如物质依赖,药物滥用(即俗称的滥药、毒瘾)、酒瘾、烟瘾、性瘾。或是持续出现特定行为(赌、暴食),网瘾、赌瘾、官瘾、财迷、工作狂、暴食症、色情狂、跟踪狂、偷窃狂、整形迷恋及购物狂等,是生理或者心理上,甚至是同时具备的一种依赖症。

英语百科

Addiction 成瘾

(重定向自Addictive drugs)


Signaling cascade in the nucleus accumbens that results in psychostimulant addiction

 
 

Note: colored text contains article links.

Nuclear pore
Nuclear membrane
Plasma membrane

Cav1.2
NMDAR
AMPAR
DRD1
DRD5
DRD2
DRD3
DRD4

Gs
Gi/o
cAMP
cAMP
PKA

CaM
CaMKII
DARPP-32
PP1
PP2B

CREB
ΔFosB
JunD
c-Fos
SIRT1
HDAC1

[Color legend 1]


This diagram depicts the signaling events in the brain's reward center that are induced by chronic high-dose exposure to psychostimulants that increase the concentration of synaptic dopamine, like amphetamine, methamphetamine, and phenethylamine. Following presynaptic dopamine and glutamate co-release by such psychostimulants,[35][36] postsynaptic receptors for these neurotransmitters trigger internal signaling events through a cAMP pathway and calcium-dependent pathway that ultimately result in increased CREB phosphorylation.[37][38][39]  Phosphorylated CREB increases levels of ΔFosB, which in turn represses the c-Fos gene with the help of corepressors;[38] c-Fos repression acts as a molecular switch that enables the accumulation of ΔFosB in the neuron.[40] A highly stable (phosphorylated) form of ΔFosB, one that persists in neurons for one or two months, slowly accumulates following repeated high-dose exposure to stimulants through this process.[41][42] ΔFosB functions as
Top: this depicts the acute expression of various Fos family proteins following an initial exposure to an addictive drug.Bottom: this illustrates increasing ΔFosB expression from repeated twice daily drug binges, where these phosphorylated (35–37 kD) ΔFosB isoforms persist in mesolimbic dopamine neurons for up to 2 months.[52][42]

Addiction is a medical condition that is characterized by compulsive engagement in rewarding stimuli, despite adverse consequences. It can be thought of as a disease or biological process leading to such behaviors. The two properties that characterize all addictive stimuli are that they are reinforcing (i.e., they increase the likelihood that a person will seek repeated exposure to them) and intrinsically rewarding (i.e., something perceived as being positive or desirable).

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更新时间:2025/6/28 17:08:04