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单词 Calreticulin
释义

Calreticulin

原声例句
Osmosis-血液肿瘤

Cells can also develop mutations in the thrombopoietin receptor, MPL, or in the chaperone protein, Calreticulin or CalR.

细胞内的促血小板生成素受体(MPL)或伴侣蛋白/钙网蛋白(CalR)也可以发生突变。

英语百科

Calreticulin

Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.

Calreticulin is a multifunctional protein that binds Ca ions (a second messenger in signal transduction), rendering it inactive. The Ca is bound with low affinity, but high capacity, and can be released on a signal (see inositol triphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum.

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更新时间:2025/6/20 1:05:16