However, there are strains who produce carbapenemases that confers resistance even to carbapenems.
不过也有一些菌株可以产生碳青霉烯酶，对碳青霉烯类也耐药。
Carbapenemase
原声例句
Osmosis-微生物
Osmosis-微生物
It's a multidrug resistant bacteria, and it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems in case of beta-lactamase production; only with carbapenems in case of ESBL production; and with colistin, tigecycline or fosfomycin in case of carbapenemases production.
肺炎克雷伯杆菌也是一种多重耐药菌，如果产生β-内酰胺酶，可以用头孢菌素、氨基糖苷类、氟喹诺酮类以及碳青霉烯类药物治疗；如果产生ESBL，可以只应用碳青霉烯类进行治疗；如果产生碳青霉烯酶，则应用多粘菌素、替加环素或磷霉素进行治疗。
英语百科
β-Lactamase
Beta-lactamases are enzymes (EC3.5.2.6) produced by bacteria(Also known as Penicillinase ) that provide resistance to β-lactam antibiotics such as penicillins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties.
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