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单词 Cholesterol desmolase
释义

Cholesterol desmolase

英语百科

Cholesterol side-chain cleavage enzyme


cholesterol + 3 NADPH + 3 H+ + 3 O2 ⇄ pregnenolone + 4-methylpentanal + 3 NADP+ + 3 H2O
Steroidogenesis, showing cholesterol side-chain cleavage enzyme at top.

Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an acronym for side-chain cleavage. P450scc is a mitochondrial enzyme that catalyzes conversion of cholesterol to pregnenolone. This is the first reaction in the process of steroidogenesis in all mammalian tissues that specialize in the production of various steroid hormones.

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更新时间:2025/6/22 10:54:34