Objective To improve the production of clavulanic acid and to genetically delete cephamycin C in the fermentation of Streptomyces clavuligerus.
目的提高棒状链霉菌的克拉维酸生产能力,去除副产物头霉素C。
Clavulanic acid
英语例句库
英语百科
Clavulanic acid
![The intermediates of the biosynthesis of Clavulanic Acid[3]](/uploads/202501/04/Clavualnic_Acid_Biosynthesis4031.png)
![Proposed mechanism of beta-lactam synthetase in the biosynthesis of clavulanic acid.[3]](/uploads/202501/04/Beta-lactam_synthetase_mechanism4031.png)
Clavulanic acid (rINN) /ˌklævjuːˈlænᵻk ˈæsᵻd/ is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.
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