芝加哥和西北运输公司（Chicago and North Western Transportation Company，缩写：CNW）是美国中西部曾经存在的一家一级铁路公司，简称为“西北铁路”。在20世纪初，拥有约5,000英里（8,000公里）的路轨，1970年代，全路共长12,000英里（19,000公里）。1859年成立，原名“芝加哥和西北铁路”，1972年，公司售予其员工后改称芝加哥和西北运输公司。在其历史上曾收购多家铁路公司如芝加哥和大西部铁路，明尼苏达和圣路易斯铁路等，使之一度成为全美国最大的铁路公司。1970年代开始，西北铁路开始放弃和出售冗余线路，至1995年，只剩约5,000英里的线路。大部分放弃和出售的线路为艾奥瓦州，伊利诺伊州，明尼苏达州，南达科他州和威斯康星州的低运量农用铁路支线。同时，西北铁路亦向达科他，明尼苏达和东方铁路等私铁商出售部分主线路段。1995年4月，公司被联合太平洋铁路收购后停止存在。

The Chicago and North Western Transportation Company (reporting markCNW) was a Class I railroad in the Midwestern United States. It was also known as the North Western. The railroad operated more than 5,000 miles (8,000 km) of track as of the turn of the 20th century, and over 12,000 miles (19,000 km) of track in seven states before retrenchment in the late 1970s. Until 1972, when the company was sold to its employees, it was named the Chicago and North Western Railway. The C&NW became one of the longest railroads in the United States as a result of mergers with other railroads, such as the Chicago Great Western Railway, Minneapolis and St. Louis Railway and others. By 1995, track sales and abandonment had reduced the total mileage back to about 5,000. The majority of the abandoned and sold lines were lightly trafficked branches in Iowa, Illinois, Minnesota, South Dakota and Wisconsin. Large line sales, such as those that resulted in the Dakota, Minnesota and Eastern Railroad further helped reduce the railroad to a mainline core with several regional feeders and branches. The company was purchased by Union Pacific Railroad (UP) in April 1995 and ceased to exist.