But cohesin really only affects looping that brings genes on the same chromosome into contact.

但cohesin实际上只影响使同一染色体上的基因接触的循环。

The cohesin acts as an " extruder" pulling two areas of DNA together and extruding out the loop from the material in between.

cohesin 充当“挤出机”，将两个 DNA 区域拉在一起，并从中间的材料中挤出环。

Even in the spaghetti state, genes move further and closer with purpose --forming loops of DNA. Many loops are bound by cohesin molecules.

即使在意大利面条状态下，基因也会有目的地移动得越来越近——形成 DNA 环。许多环被黏连蛋白分子束缚。