Macromolecular crowding

（重定向自Crowding effect）

The volume of accessible solvent (red) for two molecules of widely different sizes (black circles) at high concentrations of macromolecules (grey circles). Reducing the available volume increases the effective concentration of macromolecules.

The phenomenon of macromolecular crowding alters the properties of molecules in a solution when high concentrations of macromolecules such as proteins are present. Such conditions occur routinely in living cells; for instance, the cytosol of Escherichia coli contains about 300–7002400000000000000♠400 mg/mL of macromolecules. Crowding occurs since these high concentrations of macromolecules reduce the volume of solvent available for other molecules in the solution, which has the result of increasing their effective concentrations.

单词	Crowding effect
释义	Crowding effect 原声例句每日英语听力 \| 双语精读 2023年03月合集 The researchers reported that older adults experience a bigger crowding effect. 研究人员报告说老年人会经历更大的拥挤效应。英语百科 Macromolecular crowding （重定向自Crowding effect） The phenomenon of macromolecular crowding alters the properties of molecules in a solution when high concentrations of macromolecules such as proteins are present. Such conditions occur routinely in living cells; for instance, the cytosol of Escherichia coli contains about 300–7002400000000000000♠400 mg/mL of macromolecules. Crowding occurs since these high concentrations of macromolecules reduce the volume of solvent available for other molecules in the solution, which has the result of increasing their effective concentrations.
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