Dettelbach is a town in the district of Kitzingen in the Regierungsbezirk Unterfranken in Bavaria, Germany. It is situated on the right bank of the Main, 17 km east of Würzburg, and 7 km north of Kitzingen.

Dettelbach was first named as a settlement in 741 AD; the town was founded in 1484 AD. Dettelbach has a nearly complete medieval city wall including towers, and two remaining town gates. Dettelbach's most prominent architectural features are cobble-stoned streets with picturesque rows of half-timbered houses, and historic buildings dating as far back as the Renaissance, or even late-Gothic era.