Dexmethylphenidate
![Top: this depicts the acute expression of various Fos family proteins following an initial exposure to an addictive drug.Bottom: this illustrates increasing ΔFosB expression from repeated twice daily drug binges, where these phosphorylated (35–37 kD) ΔFosB isoforms persist in mesolimbic dopamine neurons for up to 2 months.[27][28]](/uploads/202501/08/ΔFosB_accumulation.svg3146.png)
Dexmethylphenidate (trade names Focalin, Attenade; also known as d-threo-methylphenidate (D-TMP)) is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is the active dextrorotatory enantiomer of methylphenidate.