Diffuse esophageal spasm
（重定向自Diffuse esophageal spasms）
Diffuse esophageal spasm (DES) is a condition characterized by uncoordinated contractions of the esophagus, which may cause difficulty swallowing (dysphagia) or regurgitation. In some cases, it may causes symptoms such as chest pain, similar to heart disease. The cause of DES remains unknown.