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单词 DNA microarray
释义

DNA microarray

英语例句库

Expressions of S-adenosylmethionine synthetase gene, arginase gene and oxidant stress related genes in myocardial tissue of normal and diabetic rats were assayed by DNA microarray.

在正常大鼠和糖尿病大鼠心肌组织中,以基因芯片技术测定S腺苷蛋氨酸合成酶、精氨酸酶及氧化应激相关基因的表达。

中文百科

DNA微数组

举例来说,这是一个有40,000个杂交探针点阵寡核苷酸的DNA微数组,并有放大图显示细节。
微阵列原理
Hybridization of the target to the probe.
The steps required in a microarray experiment.

DNA微数组(DNA microarray)又称DNA数组DNA芯片,比较常用的名字是基因芯片(gene chip)。是一块带有DNA微阵列(microarray)的特殊玻璃片或硅晶元片,在数平方公分之面积上布放数千或数万个核酸探针;检体中的DNA、cDNA、RNA等与探针结合后,借由荧光或电流等方式侦测。经由一次测验,即可提供大量基因串行相关信息。它是基因组学和遗传学研究的工具。研究人员应用基因芯片就可以在同一时间定量的分析大量(成千上万个)的基因表现,具有快速、精确、低成本之生物分析检验能力。

英语百科

DNA microarray DNA微阵列

Hybridization of the target to the probe.
The steps required in a microarray experiment.
Two Affymetrix chips. A match is shown at bottom left for size comparison.
A DNA microarray being printed by a robot at the University of Delaware

A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Each DNA spot contains picomoles (10 moles) of a specific DNA sequence, known as probes (or reporters or oligos). These can be a short section of a gene or other DNA element that are used to hybridize a cDNA or cRNA (also called anti-sense RNA) sample (called target) under high-stringency conditions. Probe-target hybridization is usually detected and quantified by detection of fluorophore-, silver-, or chemiluminescence-labeled targets to determine relative abundance of nucleic acid sequences in the target.

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更新时间:2025/6/19 2:26:00