Finally, DNA polymerase fills the gaps on both sides of the union and DNA ligase seals the bond.

最后，DNA聚合酶会填补两侧连接处的空白；DNA连接酶会将化学键连接起来。

Then a DNA polymerase synthesizes nucleotides to extend End 1 until it reaches a sequence that's complementary to End 2.

接着，DNA聚合酶会合成核苷酸延长End 1，直到该序列能与End 2互补为止。

When copying the mutated gene, DNA polymerase can basically lose track of which CAG it's on and accidentally add extra CAGs.

在复制突变基因时，DNA聚合酶基本上无法定位它所处的CAG位置，并由此意外添加了额外的CAG。

When copying the HTT gene, DNA polymerase can basically lose track of which CAG it's on and accidently add extra CAGs.

当HTT基因复制时，DNA聚合酶基本上无法识别校对CAG序列，意外地导致CAG序列重复。

Inside the nucleus, the DNA molecule is unzipped from around the gene by DNA polymerase.

在细胞核内，DNA 分子被 DNA 聚合酶从基因周围拉开。

The DNA polymerase, which is what makes new DNA, comes in and sees these bases and can synthesize the pairs to them.

DNA 聚合酶，就是制造新 DNA 的酶，进来看到这些碱基并能合成成对的碱基。

Then, DNA polymerase and ligase again fill in and repair the cut strand.

然后， DNA 聚合酶和连接酶再次填充并修复被切断的链。

RNA polymerases are more likely to make copying errors than DNA polymerases and therefore often make mistakes during transcription, this is why mutations in RNA viruses occur more frequently than in DNA viruses.

RNA聚合酶在复制时比DNA聚合酶更容易产生错误，因此在转录过程中经常出错，也就是为什么RNA病毒的突变比DNA病毒发生得更频繁。

He then mapped out how two other enzymes are involved: DNA polymerase, which fills in the gap, and DNA ligase, which stitches the pieces back together.

然后，他绘制了另外两种酶的参与方式：填补空白的 DNA 聚合酶和将片段缝合在一起的 DNA 连接酶。

In DNA viruses, the viral DNA enters the nucleus and uses the host's DNA polymerase to create more copies of itself as well as viral mRNA that gets translated into viral protein.

在DNA病毒中，病毒DNA进入细胞核利用宿主的DNA聚合酶完成自我复制，以及将病毒mRNA翻译成病毒蛋白质。