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单词 Micro RNA
释义

Micro RNA

原声例句
经济学人 Science and technology

The joint winners were Victor Ambros at the University of Massachusetts Medical School and Gary Ruvkun at Massachusetts General Hospital for their discovery of micro-RNA (miRNA) and its role in " post-transcriptional gene regulation" .

共同获奖者为马萨诸塞大学医学院的维克多·安布罗斯 (Victor Ambros) 和马萨诸塞州总医院的加里·鲁夫昆 (Gary Ruvkun),以表彰他们发现微小核糖核酸 (miRNA) 及其在“转录后基因调控”中的作用。

英语百科

microRNA

Diagram of micro RNA (miRNA) action with mRNA
Examples of miRNA stem-loops, with the mature miRNAs shown in red
A crystal structure of the human Drosha protein in complex with the C-terminal helices of two DGCR8 molecules (green). Drosha consists of two ribonuclease III domains (blue and orange); a double-stranded RNA binding domain (yellow); and a connector/platform domain (gray) containing two bound zinc ion (spheres). From PDB: 5B16​.

A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.

Encoded by eukaryotic nuclear DNA in plants and animals and by viral DNA in certain viruses whose genome is based on DNA, miRNAs function via base-pairing with complementary sequences within mRNA molecules. As a result, these mRNA molecules are silenced, by one or more of the following processes:

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更新时间:2025/6/20 6:55:43